COX7A2L Polyclonal Antibody

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Elabscience
Product Code: E-AB-52144
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52144-20uL20uL£125.00
Quantity:
E-AB-52144-60uL60uL£172.00
Quantity:
E-AB-52144-120uL120uL£237.00
Quantity:
E-AB-52144-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COX7A2L Polyclonal Antibody at dilution of 1:30(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COX7A2L Polyclonal Antibody at dilution of 1:30(?200)

Documents

Further Information

Abbreviation:
COX7A2L
Background:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
2.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
Purification method:
Antigen affinity purification
Target Synonym:
COX7a related protein;COX7a-related protein;COX7A2L;COX7AR;COX7R;COX7RP;Cytochrome c oxidase subunit 7A-related protein;cytochrome c oxidase subunit 7A-related protein; mitochondrial;Cytochrome c oxidase subunit 7A2 like;cytochrome c oxidase subunit VII-related protein;cytochrome c oxidase subunit VIIa polypeptide 2 like;Cytochrome c oxidase subunit VIIa related protein; mitochondrial;Cytochrome c oxidase subunit VIIa-related protein;EB1;Estrogen receptor binding CpG island;mitochondrial;SIG81
UNIProt ID:
O14548