CAPN3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52137-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52137-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52137-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52137-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CAPN3
Background:
Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human CAPN3
Purification method:
Antigen affinity purification
Target Synonym:
Calcium-activated neutral proteinase 3;calpain 3; (p94);Calpain L3;Calpain large polypeptide L3 ;Calpain p94;calpain p94; large [catalytic] subunit;calpain; large polypeptide L3;Calpain-3;CAN3;CANP 3;CANP3;CANPL3;CAPN3;LGMD 2A;LGMD2;LGMD2A;Lp82;Lp85;MGC10767;MGC11121;MGC14344;MGC4403;Muscle-specific calcium-activated neutral protease 3;muscle-specific calcium-activated neutral protease 3 large subunit;nCL-1;New calpain 1;p94
UNIProt ID:
P20807