NFKB1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52132
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52132-20uL20uL£125.00
Quantity:
E-AB-52132-60uL60uL£172.00
Quantity:
E-AB-52132-120uL120uL£237.00
Quantity:
E-AB-52132-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NFKB1 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using NFKB1 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NFKB1 Polyclonal Antibody at dilution of 1:50(?200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using NFKB1 Polyclonal Antibody at dilution of 1:50(?200)

Documents

Further Information

Abbreviation:
NFKB1
Background:
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human NFKB1
Purification method:
Antigen affinity purification
Target Synonym:
DKFZp686C01211;DNA binding factor KBF1;DNA binding factor KBF1 EBP1;DNA-binding factor KBF1;EBP 1;EBP-1;EBP1;KBF1;MGC54151;nf b;NF kappa B;NF kappaB;NF kappabeta;NF kB1;NFkappaB;NFKB 1;NFKB p105;NFKB p50;Nfkb1;NFKB1;Nuclear factor kappa B DNA binding subunit;Nuclear factor kappa-B;subunit 1;Nuclear factor NF kappa B p105 subunit;Nuclear factor NF kappa B p50 subunit;Nuclear factor NF-kappa-B p50 subunit;Nuclear factor of kappa light chain gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B cells 1;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;p105;p50;p84/NF-kappa-B1 p98;Transcription factor NFKB1
UNIProt ID:
P19838