SPI1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52113
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52113-20uL20uL£125.00
Quantity:
E-AB-52113-60uL60uL£172.00
Quantity:
E-AB-52113-120uL120uL£237.00
Quantity:
E-AB-52113-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of Mouse liver tissue lysate using SPI1 Polyclonal Antibody at dilution of 1:1600
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Western blot analysis of Mouse liver tissue lysate using SPI1 Polyclonal Antibody at dilution of 1:1600

Documents

Further Information

Abbreviation:
SPI1
Background:
SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.SPI1 (Spi-1 Proto-Oncogene) is a Protein Coding gene. Diseases associated with SPI1 include Inflammatory Diarrhea and Interdigitating Dendritic Cell Sarcoma. Among its related pathways are Validated targets of C-MYC transcriptional repression and C-MYB transcription factor network. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA binding. An important paralog of this gene is SPIB.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
31 kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human SPI1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
transcription factor spi1;31 kDa Transforming Protein;31 kDa-transforming protein;cb1086;Hematopoietic transcription factor PU.1;OF;oncogene spi1;PU.1;SFFV virus-induced murine erythroleukemia oncogene;mouse;homolog of;SFPI1;si:by184l24.2;SPI 1;SPI 1 proto oncogene;SPI A;Spi1;SPI1;Spleen focus forming virus (SFFV) proviral integration oncogene spi1;Spleen focus forming virus proviral integration oncogene spi1;Transcription factor PU.1
UNIProt ID:
P17947