CEMIP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52102-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52102-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52102-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52102-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CEMIP
Background:
Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.78 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CEMIP
Purification method:
Antigen affinity purification
Target Synonym:
IR2155535;KIAA1199 protein;OTTHUMP00000185569 ;OTTHUMP00000195036;TMEM2L;Transmembrane protein 2 like
UNIProt ID:
Q8WUJ3