TJP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52081-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52081-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52081-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52081-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TJP1
Background:
Tight junction (or zonula occludens) form the continuous intercellular barrier between epithelial and endothelial cells,which is required to separate tissue spaces and regulate selective movement of solutes across the epithelium and endothelium . ZO-1 (also known as TJP1) is a peripheral membrane phosphoprotein located on the cytoplasmic face and is expressed in tight junctions of both epithelial and endothelial cells . It binds the transmembrane proteins occludin and the claudins linking them to cytoskeletal actin . ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). It is a pivotal tight junction protein and may be involved in signalling mechanisms regulating cell proliferation and differentiation .
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human TJP1
Purification method:
Antigen affinity purification
Target Synonym:
Tight junction protein 1;Tight junction protein ZO-1;Tight junction protein ZO1;TJP1;zo-1;Zo1;ZO1;Zona occludens 1;Zona occludens 1 protein;Zona occludens protein 1;Zonula occludens 1 protein;Zonula occludens protein 1
UNIProt ID:
Q07157