MBTPS2 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-52057-20uL | 20uL | £125.00 |
Quantity:
E-AB-52057-60uL | 60uL | £172.00 |
Quantity:
E-AB-52057-120uL | 120uL | £237.00 |
Quantity:
E-AB-52057-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
MBTPS2
Background:
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
57 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:10-1:50, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human MBTPS2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
BRESEK;Endopeptidase S2P;IFAP;KFSDX;MBTP2;MBTPS2;Membrane bound transcription factor site 2 protease;membrane-bound transcription factor peptidase; site 2;membrane-bound transcription factor protease; site 2;Membrane-bound transcription factor site-2 protease;S2P;S2P endopeptidase;Site 2 protease;SREBPs intramembrane protease;Sterol regulatory element-binding proteins intramembrane protease
UNIProt ID:
O43462