PPY Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52056-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52056-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52056-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52056-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PPY
Background:
This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
11 kDa
Concentration:
2.28 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PPY
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Pancreatic polypeptide;Pancreatic polypeptide Y;Pancreatic prohormone;PNP;PP;PPY;prepro-PP (prepropancreatic polypeptide)
UNIProt ID:
P01298