CD74 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40347-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40347-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40347-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40347-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CD74
Background:
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
33,26,18 kDa
Concentration:
0.95 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:100-1:300
Immunogen:
Recombinant Human HLA class II histocompatibility antigen gamma chain protein
ObservedMW:
35 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
CD 74;CD74;CD74 antigen (invariant polypeptide of major histocompatibility complex;class II antigen-associated);CD74 antigen;CD74 molecule;CD74 molecule;major histocompatibility complex;class II invariant chain;CLIP;DHLAG;Gamma chain of class II antigens;HG2A;HLA class II histocompatibility antigen gamma chain;HLA DR antigens associated invariant chain;HLA DR gamma;HLA-DR antigens-associated invariant chain;HLA-DR-gamma;HLADG;HLADR antigens associated invariant chain;Ia antigen associated invariant chain;Ia antigen-associated invariant chain;Ia associated invariant chain;Ia gamma;Ii;Invariant polypeptide of major histocompatibility complex class II antigen associated;la-gamma;Major histocompatibility complex class II invariant chain;MHC HLA DR gamma chain;MHC HLA-DR gamma chain;p33;p35;Protein 41
UNIProt ID:
P04233