IL6R Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40344-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40344-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40344-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40344-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IL6R
Background:
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
40,51 kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:100-1:300
Immunogen:
Recombinant Human Interleukin-6 receptor subunit alpha protein
ObservedMW:
80 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
CD 126;CD126;CD126 antigen;gp80;IL 6R 1;IL 6R alpha;IL 6R;IL-6 receptor alpha chain;IL-6 receptor subunit alpha;IL-6R 1;IL-6R subunit alpha;IL-6R-alpha;IL-6RA;IL6Q;Il6r;IL6RA;IL6RA;IL6RQ;Interleukin 6 receptor;interleukin 6 receptor;alpha;Interleukin-6 receptor subunit alpha;Membrane glycoprotein 80;MGC30256
UNIProt ID:
P08887