BBC3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40332-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40332-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40332-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40332-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BBC3
Background:
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
21kDa
Concentration:
4.3mg/ml
Conjugation:
Unconjugated
Dilution:
WB:1:500-1000 IHC 1:100-1:200
Immunogen:
Recombinant Human Bcl-2-binding component 3 protein
ObservedMW:
26kDa
Purification method:
Affinity purification
Target Synonym:
BBC 3;Bbc3;BBC3;BCL 2 binding component 3;Bcl-2-binding component 3;BCL2 binding component 3;JFY 1;JFY-1;JFY1;p53 up regulated modulator of apoptosis;p53 up-regulated modulator of apoptosis;p53 Upregulated Modulator of Apoptosis;PUMA alpha;PUMA/JFY1
UNIProt ID:
Q9BXH1