EIF4EBP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40327-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40327-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40327-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40327-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
EIF4EBP1
Background:
Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1),is a member of 4EBPs family,which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E,thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors,hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1,alpha,beta and gamma.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:400
Immunogen:
Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 1 protein
Purification method:
Affinity purification
Target Synonym:
4E-BP1;4EBP1;4EBP1;BP 1;eIF4E binding protein 1;eIF4E-binding protein 1;Eif4ebp1;Eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;PHASI;Phosphorylated heat- and acid-stable protein regulated by insulin 1
UNIProt ID:
Q13541