MMP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40152-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40152-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40152-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40152-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MMP-1
Background:
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
2mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100
Immunogen:
Recombinant human Matrix metalloprotease 1 protein
Purification method:
Affinity purification
Target Synonym:
27 kDa interstitial collagenase;CLG;CLGN;collagenase;fibroblast;collagenase;interstitial;Fibroblast collagenase;Interstitial collagenase;Matrix metallopeptidase 1 (interstitial collagenase);Matrix metalloprotease 1;Matrix Metalloproteinase 1;Matrix metalloproteinase-1;MMP 1;MMP-1;MMP1;MMP1;OTTHUMP00000045866
UNIProt ID:
P03956
References
- https://www.mdpi.com/1420-3049/25/19/4499