Aβ40 Polyclonal Antibody

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Elabscience
Product Code: E-AB-40070
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-40070-20uL20uL£120.00
Quantity:
E-AB-40070-60uL60uL£160.00
Quantity:
E-AB-40070-120uL120uL£230.00
Quantity:
E-AB-40070-200uL200uL£331.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Mouse
  • Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Rat lung using Aβ40 Polyclonal Antibody at dilution of 1:50
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Immunohistochemistry of paraffin-embedded Mouse brain using Aβ40 Polyclonal Antibody at dilution of 1:50
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Immunohistochemistry of paraffin-embedded Rat lung using Aβ40 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Mouse brain using Aβ40 Polyclonal Antibody at dilution of 1:50

Documents

Further Information

Abbreviation:
Aβ40
Background:
Aβ derives from APP via proteolytic cleavage by proteases called α-, β- and γ-secretase. The α-secretase cleavage precludes the formation of Aβ, while the β- and γ-cleavages generate APP components with amyloidogenic features. Amyloid beta A4 precursor protein(APP), encoded by APP gene which locate on human chromosome 21q, is a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. APP expressed in all fetal tissues and is pronounced in brain, kidney, heart and spleen, but weak in liver. Defects in APP are the cause of Alzheimer disease type 1 (AD1). This antibody can recogniaze the N-terminus of human APP: Soluble APP-alpha and Soluble APP-beta.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
2mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100
Immunogen:
Recombinant Mouse Beta-amyloid 40 protein
Purification method:
Affinity purification
Target Synonym:
A4 amyloid protein;A4;AAA;ABETA;ABPP;AD1;AICD-50;AICD-57;AICD-59;AID(50);AID(57);AID(59);Alzheimer disease amyloid protein;Amyloid beta (A4) precursor protein;Amyloid beta A4 protein;Amyloid beta protein;Amyloid intracellular domain 50;Amyloid intracellular domain 57;Amyloid intracellular domain 59;Amyloid precursor protein;APP;APPI;Beta amyloid peptide;Beta-amyloid precursor protein;Beta-APP40;Beta-APP42;C31;Cerebral vascular amyloid peptide;CTFgamma;CVAP;Gamma-CTF(50);Gamma-CTF(57);Gamma-CTF(59);peptidase nexin II;PN 2;PN II;PN-II;PN2;PreA4;Protease nexin II;Protease nexin-II;S-APP-alpha;S-APP-beta
UNIProt ID:
P12023