FAS Polyclonal Antibody

Contact us
Elabscience
Product Code: E-AB-40063
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-40063-20uL20uL£120.00
Quantity:
E-AB-40063-60uL60uL£160.00
Quantity:
E-AB-40063-120uL120uL£230.00
Quantity:
E-AB-40063-200uL200uL£331.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western Blot analysis of Hela and Raji cells using FAS Polyclonal Antibody at dilution of 1:600
2 / 2
Immunohistochemistry of paraffin-embedded Mouse liver using FAS Polyclonal Antibody at dilution of 1:50
❮❯

Western Blot analysis of Hela and Raji cells using FAS Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Mouse liver using FAS Polyclonal Antibody at dilution of 1:50

Documents

Further Information

Abbreviation:
FAS
Background:
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
37kDa
Concentration:
2mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000, IHC 1:50-1:100
Immunogen:
Recombinant human Tumor necrosis factor receptor superfamily member 6 protein
ObservedMW:
45kDa
Purification method:
Affinity purification
Target Synonym:
ALPS 1A;ALPS1A;APO 1;Apo 1 antigen;APO 1 cell surface antigen;Apo-1 antigen;APO1;Apo1 antigen;APO1 cell surface antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;APT 1;APT1;CD 95;CD 95 antigen;CD95;CD95 antigen;Delta Fas;Delta Fas/APO 1/CD95;Delta Fas/APO1/CD95;Fas (TNF receptor superfamily;member 6);FAS 1;FAS 827dupA;Fas AMA;Fas;FAS Antigen;Fas cell surface death receptor;FAS1;FASLG receptor;FASTM;sFAS;Surface antigen APO1;TNF receptor superfamily;member 6;TNFRSF 6;TNFRSF6;TNR6;Tumor necrosis factor receptor superfamily member 6
UNIProt ID:
P25445

References

  • https://www.frontiersin.org/articles/10.3389/fonc.2021.735183/full
  • https://www.mdpi.com/1422-0067/20/3/757
  • https://onlinelibrary.wiley.com/doi/abs/10.1002/tox.22942
  • https://www.sciencedirect.com/science/article/pii/S0006291X19316687