RAPGEF1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19964-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19964-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19964-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19964-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RAPGEF1
Background:
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.32 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human RAPGEF1
Purification method:
Antigen affinity purification
Target Synonym:
C3G;C3G protein;CRK SH3 binding GNRP;CRK SH3-binding GNRP;DKFZp781P1719;GRF 2;GRF2;Guanine nucleotide releasing factor 2 (specific for crk proto oncogene);Guanine nucleotide releasing factor 2;Guanine nucleotide-releasing factor 2;OTTHUMP00000064558;Protein C3G;Rap guanine nucleotide exchange factor (GEF) 1;Rap guanine nucleotide exchange factor 1;RAPGEF 1;RAPGEF1;RPGF1
UNIProt ID:
Q13905