LDHA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19937-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19937-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19937-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19937-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LDHA
Background:
LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
37 kDa
Concentration:
1.14 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human LDHA
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Cell proliferation-inducing gene 19 protein;L lactate dehydrogenase A chain;Lactate dehydrogenase A;LDH A;LDH M;LDH muscle subunit;LDH1;LDH5;LDHA;PIG 19;PIG19;Renal carcinoma antigen NY-REN-59
UNIProt ID:
P00338
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279700/