GP6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19916-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19916-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19916-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19916-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GP6
Background:
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.14 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GP6
Purification method:
Antigen affinity purification
Target Synonym:
Glycoprotein 6;Glycoprotein VI;GP6;GPIV;GPVI;GPVI;MGC138168;Platelet collagen receptor;Platelet glycoprotein VI;Platelet glycoprotein VI precursor
UNIProt ID:
Q9HCN6