FOLR1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19878-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19878-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19878-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19878-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FOLR1
Background:
Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma .
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
2.28 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human FOLR1
Purification method:
Antigen affinity purification
Target Synonym:
adult;Adult folate binding protein;Adult folate-binding protein;FBP;Folate Receptor 1 Adult;Folate receptor 1;Folate Receptor 1 Precursor;Folate receptor adult;Folate receptor alpha;Folate receptor;FOLR;FOLR1;FOLR1;FR alpha;FR-alpha;FRalpha;KB cells FBP;MOV18;Ovarian cancer associated antigen;Ovarian tumor associated antigen;Ovarian tumor associated antigen MOv18;Ovarian tumor-associated antigen MOv18
UNIProt ID:
P15328