ACOD1 Polyclonal Antibody

Elabscience
Product Code: E-AB-19833
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19833-20uL20uL£125.00
Quantity:
E-AB-19833-60uL60uL£172.00
Quantity:
E-AB-19833-120uL120uL£237.00
Quantity:
E-AB-19833-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of Mouse heart tissue and K562 cell lysates  using ACOD1 Polyclonal Antibody at dilution of 1:400

Western blot analysis of Mouse heart tissue and K562 cell lysates  using ACOD1 Polyclonal Antibody at dilution of 1:400

Documents

Further Information

Abbreviation:
ACOD1
Background:
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
53 kDa
Concentration:
1.32 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human ACOD1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ACOD1;Aconitate decarboxylase 1;Aconitate decarboxylase;CAD;Cis aconitate decarboxylase;Immune responsive gene 1 protein homolog;Immune-responsive gene 1 protein homolog;Immunoresponsive 1 homolog (mouse);Irg1;IRG1;OC116;OPTB1;TCTIRC7
UNIProt ID:
A6NK06