MECOM Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19826-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19826-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19826-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19826-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MECOM
Background:
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.68 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human MECOM
Purification method:
Antigen affinity purification
Target Synonym:
Ecotropic Virus Integration Site 1 Protein Homolog;MDS1 And EVI1 Complex Locus Protein;PR Domain 3;EVI1;MDS1;MDS1 And EVI1 Complex Locus Protein EVI1;MDS1 And EVI1 Complex Locus Protein MDS1;Ecotropic Viral Integration Site 1;Myelodysplasia Syndrome 1 Protein;Zinc Finger Protein Evi1;Oncogene EVI1;AML1-EVI-1;MDS1-EVI1;RUSAT2;KMT8E;PRDM3
UNIProt ID:
Q03112