KLF1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19799-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19799-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19799-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19799-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
KLF1
Background:
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100, ELISA 1:2000-1:5000
Immunogen:
Synthetic peptide of human KLF1
Purification method:
Antigen affinity purification
Target Synonym:
CDAN4;EKLF;EKLF PEN;Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor);Erythroid krueppel-like transcription factor;Erythroid Kruppel like factor;Erythroid specific transcription factor EKLF;HBFQTL6;Human erythroid-specific transcription factor EKLF mRNA complete cds;INLU;Klf1;KLF1;Krueppel-like factor 1;Kruppel like factor 1 (erythroid)
UNIProt ID:
Q13351