FBXO32 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-19785-20uL | 20uL | £125.00 |
Quantity:
E-AB-19785-60uL | 60uL | £172.00 |
Quantity:
E-AB-19785-120uL | 120uL | £237.00 |
Quantity:
E-AB-19785-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
FBXO32
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.44 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human FBXO32
Purification method:
Antigen affinity purification
Target Synonym:
4833442G10Rik;AI430017;Atrogin 1 ;Atrogin-1;ATROGIN1;Atrophy gene 1;F box only protein 32;F-box only protein 32;F-box protein 32;FBX32;fbxo25;FBXO32;FLJ32424;MAFbx;MGC108443;MGC137646;MGC33610 ;Muscle atrophy F box;Muscle atrophy F box protein;Muscle atrophy F-box protein
UNIProt ID:
Q969P5