HIST1H2BA Polyclonal Antibody

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Elabscience
Product Code: E-AB-19784
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19784-20uL20uL£125.00
Quantity:
E-AB-19784-60uL60uL£172.00
Quantity:
E-AB-19784-120uL120uL£237.00
Quantity:
E-AB-19784-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(?200)
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(?200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(?200)

Documents

Further Information

Abbreviation:
HIST1H2BA
Background:
The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
14 kDa
Concentration:
1.98 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human HIST1H2BA
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
HIST1H2BA;testis;bA317E16.3;H2B;H2B histone family member U;H2B histone family member U testis specific;H2B histone family;member U;(testis specific);H2B testis;H2B1A;H2BFU;H2BT;HIST1H2BA;Histone 1;H2ba;Histone cluster 1 H2ba;Histone H2B;Histone H2B testis;Histone H2B type 1 A;Histone H2B type 1-A;Histone H2B type 1A;STBP;Testis specific histone H2B;Testis-specific histone H2B;TSH 2B;TSH2B;TSH2B.1
UNIProt ID:
Q96A08