PNPO Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19759-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19759-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19759-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19759-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PNPO
Background:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
30 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PNPO
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
EC 1.4.3.5;FLJ10535;PDXPO;PNPO;PNPO;Pyridoxal 5' phosphate synthase;pyridoxamine 5' phosphate oxidase;Pyridoxamine phosphate oxidase ;Pyridoxamine-phosphate oxidase;pyridoxine 5' phosphate oxidase;Pyridoxine-5'-phosphate oxidase
UNIProt ID:
Q9NVS9