MORF4L2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-19745
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19745-20uL20uL£125.00
Quantity:
E-AB-19745-60uL60uL£172.00
Quantity:
E-AB-19745-120uL120uL£237.00
Quantity:
E-AB-19745-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of 293T Hela and A431 cell lysates using MORF4L2 Polyclonal Antibody at dilution of 1:500
2 / 2
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MORF4L2 Polyclonal Antibody at dilution of 1:25(?200)
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Western blot analysis of 293T Hela and A431 cell lysates using MORF4L2 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MORF4L2 Polyclonal Antibody at dilution of 1:25(?200)

Documents

Further Information

Abbreviation:
MORF4L2
Background:
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
32 kDa
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human MORF4L2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
KIAA0026 ;MO4L2;MORF related gene X protein;MORF-related gene X protein;Morf4l2;MORFL2;Mortality factor 4 like protein 2;Mortality factor 4-like protein 2;MRGX;MSL3 2 protein;Protein MSL3-2;Transcription factor like protein MRGX ;Transcription factor-like protein MRGX
UNIProt ID:
Q15014