COL17A1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-19718
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19718-20uL20uL£125.00
Quantity:
E-AB-19718-60uL60uL£172.00
Quantity:
E-AB-19718-120uL120uL£237.00
Quantity:
E-AB-19718-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using COL17A1 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COL17A1 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using COL17A1 Polyclonal Antibody at dilution of 1:50(?200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COL17A1 Polyclonal Antibody at dilution of 1:50(?200)

Documents

Further Information

Abbreviation:
COL17A1
Background:
COL17A1 (Collagen Type XVII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL17A1 include Epidermolysis Bullosa, Junctional, Non-Herlitz Type and Epithelial Recurrent Erosion Dystrophy. Among its related pathways are Collagen chain trimerization and Phospholipase-C Pathway. An important paralog of this gene is COL6A1.This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.38 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human COL17A1
Purification method:
Antigen affinity purification
Target Synonym:
180 kDa bullous pemphigoid antigen 2;Alpha 1 type XVII collagen;BA16H23.2;BP 180;BP180;BPA 2;BPAG 2;BPAG2;Bullous pemphigoid antigen 2;COL17A1;Collagen 17;Collagen alpha 1 XVII chain;Collagen alpha 1(XVII) chain;Collagen alpha1 XVII chain;Collagen type XVII alpha 1;Collagen XVII alpha 1 polypeptide;CollagenXVII;Epidermolysis bullosa junctional localisata variant;FLJ60881;KIAA0204;LAD 1;LAD1
UNIProt ID:
Q9UMD9