CDH12 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19682-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19682-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19682-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19682-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CDH12
Background:
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.74 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CDH12
Purification method:
Antigen affinity purification
Target Synonym:
Br cadherin;BR-cadherin;Brain cadherin;CAD12_HUMAN;cadherin 12 (N cadherin 2);Cadherin 12;Cadherin 12 precursor;Cadherin 12 type 2 (N cadherin 2);Cadherin 12 type 2;Cadherin neural type 2;Cadherin-12;CDH12;CDHB;FLJ34857;N cadherin 2;N-cadherin 2;Neural type cadherin 2;Neuronal cadherin 2
UNIProt ID:
P55289