CAD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19652-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19652-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19652-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19652-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CAD
Background:
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CAD
Purification method:
Antigen affinity purification
Target Synonym:
Aspartate carbamoyltransferase;Aspartate transcarbamylase;CAD protein;CAD trifunctional protein;Carbamoyl phosphate synthetase 2;Carbamoyl-phosphate synthetase 2 aspartate transcarbamylase and dihydroorotase;CPSase ATCase DHOase;Dihydroorotase;Glutamine dependent carbamoyl phosphate synthase;Multifunctional protein CAD
UNIProt ID:
P27708