CA5B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19648-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19648-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19648-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19648-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CA5B
Background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles.CA5B (Carbonic Anhydrase 5B) is a Protein Coding gene. Diseases associated with CA5B include Heart Conduction Disease and Heart Septal Defect. Among its related pathways are Nitrogen metabolism and Metabolism. GO annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA5A.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CA5B
Purification method:
Antigen affinity purification
Target Synonym:
CA VB;Carbonate dehydratase VB;Carbonic anhydrase 5B;mitochondrial;Carbonic anhydrase VB;Carbonic anhydrase VB;mitochondrial
UNIProt ID:
Q9Y2D0