HUWE1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19540-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19540-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19540-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19540-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HUWE1
Background:
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:10-1:50, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human HUWE1
Purification method:
Antigen affinity purification
Target Synonym:
ARF binding protein 1;ARF BP1;ARF-binding protein 1;ARF-BP1;BJ-HCC-24 tumor antigen;E3 ubiquitin protein ligase HUWE1;E3 ubiquitin-protein ligase HUWE1;HECT;HECT domain protein LASU1;HECT UBA and WWE domain containing protein 1;HectH9;Homologous to E6AP carboxyl terminus homologous protein 9;Huwe1;HUWE1;Ib772;Large structure of UREB1;LASU1;Mcl 1 ubiquitin ligase E3;Mcl-1 ubiquitin ligase E3;Mule;UBA and WWE domain-containing protein 1;Upstream regulatory element-binding protein 1;URE-B1;URE-binding protein 1;UREB1
UNIProt ID:
Q7Z6Z7