SPTA1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-19527
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19527-20uL20uL£125.00
Quantity:
E-AB-19527-60uL60uL£172.00
Quantity:
E-AB-19527-120uL120uL£237.00
Quantity:
E-AB-19527-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of Mouse heart tissue lysate using SPTA1 Polyclonal Antibody at dilution of 1:550
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Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SPTA1 Polyclonal Antibody at dilution of 1:80(?200)
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Western blot analysis of Mouse heart tissue lysate using SPTA1 Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SPTA1 Polyclonal Antibody at dilution of 1:80(?200)

Documents

Further Information

Abbreviation:
SPTA1
Background:
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
280 kDa
Concentration:
1.7 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:60-1:450, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human SPTA1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Alpha I spectrin;EL 2;EL2;Elliptocytosis 2;Elliptocytosis2;Erythrocyte alpha spectrin;erythrocyte;Erythroid alpha spectrin;Erythroid alpha-spectrin;Erythroid spectrin alpha;HPP;HS3;Spectrin alpha chain;Spectrin alpha chain erythrocyte;Spectrin alpha erythrocytic 1;SPH3;SPTA 1;SPTA;SPTA1;SPTA1
UNIProt ID:
P02549