IL6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19453-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19453-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19453-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19453-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IL6
Background:
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells,T-cells,hepatocytes,hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine,a cytokine produced from muscle,and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally,IL-6 is involved in hematopoiesis,bone metabolism,and cancer progression,and has been defined an essential role in directing transition from innate to acquired immunity.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
24 kDa
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human IL6
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Interleukin BSF 2;B cell differentiation factor;B cell stimulatory factor 2;B-cell stimulatory factor 2;BSF 2;BSF-2;BSF2;CDF;CTL differentiation factor;Hepatocyte stimulatory factor;HGF;HSF;Hybridoma growth factor;Hybridoma growth factor Interferon beta-2;IFN-beta-2;IFNB2;IL 6;IL-6;IL6;IL6;Interferon beta 2;Interferon beta-2;Interleukin 6;Interleukin 6 (interferon beta 2);Interleukin BSF 2;Interleukin-6
UNIProt ID:
P05231
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068511/