DPPA4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19445-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19445-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19445-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19445-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
DPPA4
Background:
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.56 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human DPPA4
Purification method:
Antigen affinity purification
Target Synonym:
2410091M23Rik;Developmental pluripotency associated 4;Developmental pluripotency associated protein 4;Developmental pluripotency-associated protein 4;Dppa 4;DPPA4;DPPA4;FLJ10713
UNIProt ID:
Q7L190