PEG3 Polyclonal Antibody

Elabscience
Product Code: E-AB-19429
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19429-20uL20uL£125.00
Quantity:
E-AB-19429-60uL60uL£172.00
Quantity:
E-AB-19429-120uL120uL£237.00
Quantity:
E-AB-19429-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human gastric cancer tissue  using PEG3 Polyclonal Antibody at dilution of 1:45(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using PEG3 Polyclonal Antibody at dilution of 1:45(?200)

Immunohistochemistry of paraffin-embedded Human gastric cancer tissue  using PEG3 Polyclonal Antibody at dilution of 1:45(?200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using PEG3 Polyclonal Antibody at dilution of 1:45(?200)

Documents

Further Information

Abbreviation:
PEG3
Background:
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PEG3
Purification method:
Antigen affinity purification
Target Synonym:
PEG3;KIAA0287;ZSCAN24;Paternally-expressed gene 3 protein;Zinc finger and SCAN domain-containing protein 24
UNIProt ID:
Q9GZU2