DDC Polyclonal Antibody
Code | Size | Price |
---|
E-AB-19409-20uL | 20uL | £125.00 |
Quantity:
E-AB-19409-60uL | 60uL | £172.00 |
Quantity:
E-AB-19409-120uL | 120uL | £237.00 |
Quantity:
E-AB-19409-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
DDC
Background:
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
54 kDa
Concentration:
1.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human DDC
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
AADC;Aromatic L Amino Acid Decarboxylase;Aromatic-L-amino-acid decarboxylase;DDC;DDC_HUMAN;DOPA decarboxylase (aromatic L-amino acid decarboxylase);DOPA decarboxylase
UNIProt ID:
P20711