COX17 Polyclonal Antibody

COX17

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

1.2 mg/mL

Unconjugated

IHC 1:30-1:150, ELISA 1:2000-1:10000

Synthetic peptide of human COX17

Antigen affinity purification

COX 17;COX17;COX17 cytochrome c oxidase assembly homolog (S. cerevisiae);COX17 cytochrome c oxidase assembly homolog;COX17 homolog cytochrome c oxidase assembly protein;COX17;cytochrome c oxidase assembly protein cox17 homolog;Cytochrome c oxidase copper chaperone;Human homolog of yeast mitochondrial copper recruitment;MGC104397;MGC117386;OTTHUMP00000215284;OTTHUMP00000215285

Q14061