GLS Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19340-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19340-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19340-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19340-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GLS
Background:
GLS,also named as GLS1 and KIAA0838,belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-,glutamate-,and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells,in accordance with measurements of glutaminase activity,and had the same molecular mass of approx. 63 kDa. The bands for both cell lines are clearly different in size from both rat liver glutaminase (58 kDa) and rat kidney glutaminase (65 kDa). It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. It has 3 isoforms named as KGA,GAM,GAC.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
73 kDa
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GLS
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
AAD20;DKFZp686O15119;FLJ10358;GAC;GAM;GLS;GLS1;GLSK;Glutaminase C;Glutaminase kidney isoform;Glutaminase phosphate activated;K-glutaminase;KGA;KIAA0838;L-glutamine amidohydrolase;mitochondrial
UNIProt ID:
O94925