PTEN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19312-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19312-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19312-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19312-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PTEN
Background:
PTEN (also designated MMAC1),products of tumor suppressor genes,are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors,such as brain,breast,kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
47 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PTEN
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
10q23del;BZS;DEC;GLM2;MGC11227;MHAM;MMAC1;MMAC1 phosphatase and tensin homolog deleted on chromosome 10;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;Phosphatase and tensin like protein;Phosphatidylinositol 3;4;5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN;Pten;PTEN;PTEN1;TEP1
UNIProt ID:
P60484
References
- https://www.sciencedirect.com/science/article/pii/S0168822722008804