PAX5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19303-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19303-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19303-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19303-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PAX5
Background:
PAX5,also named B-cell specific activator protein (BSAP),is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B,pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL,PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PAX5
Purification method:
Antigen affinity purification
Target Synonym:
B cell lineage specific activator;B cell lineage specific activator protein;B cell specific activator protein;B cell specific transcription factor;B-cell-specific transcription factor;BSAP;EBB-1;KLP;Paired box 5;Paired box gene 5 (B cell lineage specific activator protein);Paired box gene 5 (B cell lineage specific activator);Paired box gene 5;Paired box homeotic gene 5;Paired box protein Pax 5;Paired box protein Pax-5;Paired domain gene 5;PAX 5;PAX5;PAX5;Transcription factor PAX 5
UNIProt ID:
Q02548