PPBP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19288-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19288-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19288-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19288-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PPBP
Background:
PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Colloid Adenoma. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. GO annotations related to this gene include growth factor activity and glucose transmembrane transporter activity. An important paralog of this gene is CXCL1. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
14 kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:25-1:100, ELISA 1:2000-1:10000
Immunogen:
Synthetic peptide of human PPBP
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
B TG1;Beta TG;Beta thromboglobulin;Beta-TG;C-X-C motif chemokine 7;Chemokine (C X C motif) ligand 7;Connective tissue activating peptide III;CTAP 3;CTAP III;CTAP-III;CTAP-III(1-81);CTAP3;CTAPIII;CXC chemokine ligand 7;CXCL 7;CXCL7;CXCL7;LA PF 4;LA-PF4;LDGF;Leukocyte derived growth factor;Leukocyte-derived growth factor;Low-affinity platelet factor IV;Macrophage-derived growth factor;MDGF;NAP 2;NAP-2;NAP-2(1-63);NAP-2(1-66);NAP-2(73);NAP-2(74);Neutrophil activating peptide 2;Neutrophil-activating peptide 2(1-63);PBP;Platelet basic protein;PPBP;Pro platelet basic protein (chemokine (C-X-C motif) ligand 7);Pro platelet basic protein;SCYB7;Small inducible cytokine subfamily B member 7;Small-inducible cytokine B7;TC1;TC2;TGB;TGB1;THBGB;THBGB1;Thrombocidin 1;Thrombocidin 2;Thromboglobulin;beta-1
UNIProt ID:
P02775