SPACA1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19214-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19214-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19214-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19214-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SPACA1
Background:
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human SPACA1
Purification method:
Antigen affinity purification
Target Synonym:
SACA1;SAMP32;SPACA1;Sperm acrosomal membrane-associated protein 32;Sperm acrosome membrane-associated protein 1
UNIProt ID:
Q9HBV2