TNNT1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19204-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19204-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19204-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19204-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TNNT1
Background:
This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.32 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human TNNT1
Purification method:
Antigen affinity purification
Target Synonym:
ANM;MGC104241;NEM5;Skeletal;Slow ;slow skeletal muscle;Slow skeletal muscle troponin T;sTnT;Tnnt1;TNNT1;TNT;TnTs;Troponin T;Troponin T slow skeletal muscle;Troponin T type 1 (skeletal slow);troponin T1 skeletal slow;Troponin T1; slow skeletal type
UNIProt ID:
P13805