KCNIP3 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-19200-20uL | 20uL | £125.00 |
Quantity:
E-AB-19200-60uL | 60uL | £172.00 |
Quantity:
E-AB-19200-120uL | 120uL | £237.00 |
Quantity:
E-AB-19200-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
KCNIP3
Background:
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.62 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human KCNIP3
Purification method:
Antigen affinity purification
Target Synonym:
4933407H12Rik;A type potassium channel modulatory protein 3;A-type potassium channel modulatory protein 3;AI413860;Calsenilin;CSEN;CSEN;DRE antagonist modulator;DRE-antagonist modulator;DREAM;EF hand transcription factor;KCHIP 3;KChIP3;KCNIP 3;Kcnip3;Kv channel interacting protein 3;Kv channel-interacting protein 3;MGC18289;Potassium channel interacting protein 3;R74849
UNIProt ID:
Q9Y2W7