PPM1M Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19190-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19190-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19190-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19190-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PPM1M
Background:
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.74 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PPM1M
Purification method:
Antigen affinity purification
Target Synonym:
FLJ32332;PP2C eta;PP2C-eta;PP2CE;PP2Ceta;PPM1M;PPM1M;protein phosphatase 1M (PP2C domain containing);Protein phosphatase 1M;Protein phosphatase 2C isoform eta
UNIProt ID:
Q96MI6