MRPL22 Polyclonal Antibody

MRPL22

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.

PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

0.9 mg/mL

Unconjugated

IHC 1:50-1:200, ELISA 1:5000-1:10000

Fusion protein of human MRPL22

Antigen affinity purification

MRPL22;39S ribosomal protein L22;39S ribosomal protein L22 mitochondrial precursor;39S ribosomal protein L25;39S ribosomal protein L25; mitochondrial;E030011D16Rik;HSPC158;L22mt;L25mt;mitochondrial;mitochondrial ribosomal protein L22;MRP L22;MRP L25;MRP-L22;MRP-L25;Mrpl22;RM22;RPML25

Q9NWU5