GCSH Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19143-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19143-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19143-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19143-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GCSH
Background:
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human GCSH
Purification method:
Antigen affinity purification
Target Synonym:
GCE;GCSH;GCSH;Glycine cleavage system H protein;Glycine cleavage system H protein mitochondrial;Glycine cleavage system protein H (aminomethyl carrier);Glycine cleavage system protein H;Lipoic acid containing protein;mitochondrial;Mitochondrial glycine cleavage system H protein;NKH
UNIProt ID:
P23434