CD59 Polyclonal Antibody

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Elabscience
Product Code: E-AB-19113
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-19113-20uL20uL£125.00
Quantity:
E-AB-19113-60uL60uL£172.00
Quantity:
E-AB-19113-120uL120uL£237.00
Quantity:
E-AB-19113-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD59 Polyclonal Antibody at dilution of 1:160(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD59 Polyclonal Antibody at dilution of 1:160(?200)

Documents

Further Information

Abbreviation:
CD59
Background:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.38 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human CD59
Purification method:
Antigen affinity purification
Target Synonym:
16.3A5;1F5;1F5 antigen;20 kDa homologous restriction factor;CD 59;CD_antigen=CD59;CD59;CD59 antigen;CD59 antigen complement regulatory protein ;CD59 antigen p18 20;CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5;EJ16;EJ30;EL32 and G344);CD59 glycoprotein;CD59 molecule;CD59 molecule complement regulatory protein;CD59;Cd59a;Complement regulatory protein;EJ16;EJ30;EL32;FLJ38134;FLJ92039;G344;HRF 20;HRF-20;HRF20;Human leukocyte antigen MIC11;Ly 6 like protein;Lymphocytic antigen CD59/MEM43;MAC inhibitory protein;MAC IP;MAC-inhibitory protein;MAC-IP;MACIF;MACIP;MEM43;MEM43 antigen;Membrane attack complex (MAC) inhibition factor;Membrane attack complex inhibition factor;Membrane inhibitor of reactive lysis;MGC2354;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18 20;Protectin;Surface antigen recognized by monoclonal 16.3A5;T cell activating protein
UNIProt ID:
P13987