ELOC Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19103-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19103-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19103-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19103-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ELOC
Background:
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ELOC
Purification method:
Antigen affinity purification
Target Synonym:
Elongin C;Transcription Elongation Factor B (SIII); Polypeptide 1 (15kDa; Elongin C);RNA Polymerase II Transcription Factor SIII Subunit C;Transcription Elongation Factor B Polypeptide 1;Transcription Elongation Factor B Subunit 1;Elongin 15 KDa Subunit;SIII P15.
UNIProt ID:
Q15369