PCBD1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-19099-20uL | 20uL | £125.00 |
Quantity:
| E-AB-19099-60uL | 60uL | £172.00 |
Quantity:
| E-AB-19099-120uL | 120uL | £237.00 |
Quantity:
| E-AB-19099-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PCBD1
Background:
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
12 kDa
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PCBD1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
4 alpha hydroxy tetrahydropterin dehydratase;4-alpha-hydroxy-tetrahydropterin dehydratase;6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;DCoH;Dimerization cofactor of hepatic nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1-alpha;Dimerization cofactor of HNF1;Dimerizing cofactor for HNF1;PCBD 1;PCBD;PCBD1;PCD;Phenylalanine hydroxylase stimulating protein;Phenylalanine hydroxylase-stimulating protein;PHS;PHS;Pterin 4 alpha carbinolamine dehydratase;Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;Pterin carbinolamine dehydratase;Pterin-4-alpha-carbinolamine dehydratase
UNIProt ID:
P61457